Molecular Nociception Group
James J Cox PhD, John N Wood FRS, Jing Zhao MD PhD
Our research
The twenty-first century has seen a revolution in our understanding of the receptor systems and regulatory pathways that underlie the responses of nociceptors to the occurrence of tissue damage. This has important implications for human health and disease.
We collaborate with research groups in Europe, the United States, Korea, Japan, and Australia, using transgenic mouse models, natural products, and cloned genes to explore the physiology of pain perception.ÌýThe systems we study have a broad relevance to understanding how the nervous system works in terms of synaptic plasticity, responses to environmental stimuli, sensation, and behaviour.
Lab Manager
Sam Gossage
Recent Post-Doctoral Fellows
- Sascha R.A. Alles PhD
- Ali Bangash MD PhD
- Shafaq Sikandar PhD
- Ana Luiz PhD
- Edward C. Emery PhD
- John Linley PhD
- Naxi Tian PhD
- Manuel Arcangeletti PhD
- Federico Iseppon PhD
Recent PhD Students
- 2014ÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌý ÌýSam Shepherd
- 2014 ÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌý ÌýAlexandros KanellopoulosÌý
- 2015ÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌý Man-Cheung Lee
- 2015ÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌý JennyÌý KoenigÌýÌýÌýÌý
- 2015ÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌý ÌýShengnan LiÌý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý Ìý
- 2016Ìý Ìý Ìý ÌýÌýÌýÌýÌýÌýÌýÌý ÌýÌýSonia Santana-VarelaÌýÌýÌýÌýÌý
- 2019ÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌý ÌýLarissa de Clauser
- 2020ÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌý Donald MacDonald
- 2020ÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌý Alice ÌýFuller
- 2023 ÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌý ÌýRayan Haroun ÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌý
- 2023 ÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌý ÌýClarissa ButtiÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌýÌý
Ìý
Selected publications
Swanton C, Bernard E, Abbosh C, André F, Auwerx J, Balmain A, Bar-Sagi D, Bernards R, Bullman S, DeGregori J, Elliott C, Erez A, Evan G, Febbraio MA, Hidalgo A, Jamal-Hanjani M, Joyce JA, Kaiser M, Lamia K, Locasale JW, Loi S, Malanchi I, Merad M, Musgrave K, Patel KJ, Quezada S, Wargo JA, Weeraratna A, White E, Winkler F, Wood JN, Vousden KH, Hanahan D. Cell. 2024 Mar 28;187(7):1589-1616
Pak S, Ryu H, Lim S, Nguyen TL, Yang S, Kang S, Yu YG, Woo J, Kim C, Fenollar-Ferrer C, Wood JN, Lee MO, Hong GS, Han K, Kim TS, Oh U. Cell Rep. 2024 Jun 7;43(6):114334.
Lischka A, Eggermann K, Record CJ, Dohrn MF, LaÅ¡Å¡uthová P, Kraft F, Begemann M, Dey D, Eggermann T, Beijer D, Å oukalová J, Laura M, Rossor AM, Mazanec R, Van Lent J, Tomaselli PJ, Ungelenk M, Debus KY, Feely SME, Gläser D, Jagadeesh S, Martin M, Govindaraj GM, Singhi P, Baineni R, Biswal N, Ibarra-RamÃrez M, Bonduelle M, Gess B, Romero Sánchez J, Suthar R, Udani V, Nalini A, Unnikrishnan G, Marques W Junior, Mercier S, Procaccio V, Bris C, Suresh B, Reddy V, Skorupinska M, Bonello-Palot N, Mochel F, Dahl G, Sasidharan K, Devassikutty FM, Nampoothiri S, Rodovalho Doriqui MJ, Müller-Felber W, Vill K, Haack TB, Dufke A, Abele M, Stucka R, Siddiqi S, Ullah N, Spranger S, Chiabrando D, Bolgül BS, Parman Y, Seeman P, Lampert A, Schulz JB, Wood JN, Cox JJ, Auer-Grumbach M, Timmerman V, de Winter J, Themistocleous AC, Shy M, Bennett DL, Baets J, Hübner CA, Leipold E, Züchner S, Elbracht M, Çakar A, Senderek J, Hornemann T, Woods CG, Reilly MM, Kurth I. Brain. 2023 Dec 1;146(12):4880-4890.
Haroun R, Gossage SJ, Luiz AP, Arcangeletti M, Sikandar S, Zhao J, Cox JJ, Wood JN. eNeuro. 2023 Sep 26;10(9):ENEURO.0151-23.2023.
Fuller AM, Luiz A, Tian N, Arcangeletti M, Iseppon F, Sexton JE, Millet Q, Caxaria S, Ketabi N, Celik P, Wood JN, Sikandar S. Brain. 2023 Oct 3;146(10):4033-4039.
Mikaeili H, Habib AM, Yeung CW, Santana-Varela S, Luiz AP, Panteleeva K, Zuberi S, Athanasiou-Fragkouli A, Houlden H, Wood JN, Okorokov AL, Cox JJ. Brain. 2023 Sep 1;146(9):3851-3865.
Caxaria S, Bharde S, Fuller AM, Evans R, Thomas B, Celik P, Dell'Accio F, Yona S, Gilroy D, Voisin MB, Wood JN, Sikandar S. Proc Natl Acad Sci U S A. 2023 Apr 25;120(17):e2211631120
Iseppon F, Luiz AP, Linley JE, Wood JN. eNeuro. 2023 Feb 21;10(2):ENEURO.0395-22.2022
Schmidt M, Sondermann JR, Gomez-Varela D, Çubuk C, Millet Q, Lewis MJ, Wood JN, Zhao J. Front Mol Neurosci. 2022 Oct 11;15:1002842.
Lischka A, Lassuthova P, Çakar A, Record CJ, Van Lent J, Baets J, Dohrn MF, Senderek J, Lampert A, Bennett DL, Wood JN, Timmerman V, Hornemann T, Auer-Grumbach M, Parman Y, Hübner CA, Elbracht M, Eggermann K, Geoffrey Woods C, Cox JJ, Reilly MM, Kurth I. Nat Rev Dis Primers. 2022 Jun 16;8(1):41
MacDonald DI, Sikandar S, Weiss J, Pyrski M, Luiz AP, Millet Q, Emery EC, Mancini F, Iannetti GD, Alles SRA, Arcangeletti M, Zhao J, Cox JJ, Brownstone RM, Zufall F, Wood JN. Neuron. 2021 May 5;109(9):1497-1512
MacDonald DI, Luiz AP, Iseppon F, Millet Q, Emery EC, Wood JN. Brain. 2021 Jul 28;144(6):1711-1726
Facilities
Related programmes
Researchers within the Wolfson Institute for Biomedical Research contribute to several distinguished taught courses at 911±¬ÁÏÍø.