911±¬ÁÏÍø

XClose

Safety Services

Home
Menu

Thiols

A thiol is a compound that contains the –SH functional group, which is the sulfur analogue of a hydroxyl or alcohol group.

Why this substance is hazardous?​

Thiols orÌýmercaptan, although toxic are often not dangerous in the quantities used in experiments.ÌýHowever, thiols are odorants and are detectable to the human nose at as little as 2-parts per billion. AtÌýthese concentrations, there are unlikely to cause chronic health problems but are classified as offensiveÌýdue to the stench. This means that;​

  • ​It is against the Environment Act to release them as the smell itself is considered a statutoryÌýnuisanceÌý​
  • The smell can cause some people to react adversely, common reactions are headaches and nauseaÌý​
  • Due to uses of thiols as an additive to natural gas supplies, accidental release can causeÌýwidespread disruptions as it can be confused as a leak from the supply.​

±«²õ±ð²õ​

The mostÌýwell-knownÌýuse for thiols is as the odour in natural gas, they feature heavily in research due to their biological importance and thiols can be used to make disulphides andÌýsulphonicÌýacids.
B-MercaptoethanolÌýis an antioxidant.


Recommended control measures​

Minimise the risk of exposure

  • Always assess where the work is going to happen, thiols usually have high volatility so vapour will be produced.​
  • Do not work directly in a fume cupboard without filtration, either on the fume cupboard or on theÌýexperiment, as theÌýsmell will just be transported rather than removed.​

​S³Ù´Ç°ù²¹²µ±ð

Due to the volatility, store in a manner that will expect vapour to be produced and controlledÌý​

Use

  • Always inform the people working in the area and the department that works with thiols is to goÌýahead, in case of accident release.​
  • When possible ensure that all thiol vapour is caught and re-oxidised at the source. ​

Health surveillanceÌý​

None.

Chemical safety library


> Read more about control measures for chemicals in our chemical safety libraryÌý

Other smelly chemicalsÌý​


Chemicals that could be classed as​Ìýstatutory nuisances and shouldÌý​ follow the same control measures if​ used or produced​​:

  • FruitÌýfly food – Phenolic compounds​
  • AutoclavedÌýculture plates (meat and blood)​
  • Trans-4,5- epoxy-E-2-decenal​
  • ¹ó´Ç°ù³¾²¹±ô»å±ð³ó²â»å±ð​
  • CadaverineÌý–ÌýdecarboxylatedÌýlysine​
  • ²Ô-µþ³Ü³Ù²¹²Ô´Ç±ô​
  • SeleniumÌýand tellurium compounds (like sulphur but lowerÌýon the periodic table)​
  • ±Ê²â°ù¾±»å¾±²Ô±ð​
  • TerpenesÌýandÌýterpenoidsÌý(odour from cannabis)Ìý​
  • AnythingÌýsmelly produced that is unreasonable andÌýsubstantially interferes with the use of a work area at 911±¬ÁÏÍø​

Last updated: Tuesday, June 23, 2020