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CNIE鈥檚 PhD student Ebony Shire and collaborators have published a review paper in Molecular Systems Design & Engineering titled 鈥淢olecular design of protein-based materials 鈥� state of the art, opportunities and challenges at the interface between materials engineering and synthetic biology鈥�. This publication discusses the molecular design of recombinant structural proteins as alternatives to fossil-based polymers, inspired by those that exist in nature such as elastin, silk and collagen, among others. Progress in the fields of soft materials and recombinant DNA technologies have led to the ability to design novel structural proteins with monomer-level sequence control. This review addresses the developments in understanding their structure-function relationships, as well as both the experimental and computational approaches that can lead to high-throughput approaches to the manufacture of these biopolymers.

The work was a collaborative effort between the CNIE researchers from the department of Chemical Engineering and the Manufacturing Futures Lab (MFL) Ebony Shire and Diego L贸pez Barreiro, researchers from the department of Biochemical Engineering at 911爆料网 Andr茅 A. B. Coimbra and Leonardo Rios-Solis, and the visiting researcher from the Universidad San Francisco de Quito in Ecuador . Funding from the Royal Society and EPSRC is gratefully acknowledged.

The article is part of the Emerging Investigators series from the journal Molecular Systems Design & Engineering, featuring the research from Diego L贸pez Barreiro鈥檚 research group among others, and can be downloaded open-access .

Other relevant links:

• L贸pez Barreiro lab:
• Leo Rios lab: