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Heart and Circulation (PHOL0007)

Key information

Faculty
Faculty of Life Sciences
Teaching department
Division of Biosciences
Credit value
30
Restrictions
PHOL0001/2 and PHOL0003/0004 or years 1 and 2 MBBS or equivalent are prerequisites for this module. In exceptional circumstances we may consider students who have taken other potentially relevant modules. The module cannot accommodate more than 90 students. Places will be allocated based on previous academic performance in relevant subjects.
Timetable

Alternative credit options

There are no alternative credit options available for this module.

Description

“Heart and Circulation” builds upon your primary knowledge of the heart and circulation. Contemporary views of cardiac and vascular physiology will be considered. The module will develop your understanding of cardiac and vascular function in relation to cellular mechanisms, with an emphasis on translating this to the human subject and the pathology of various cardiovascular diseases.

As well as formal lectures you will learn through small group tutorial sessions on preparing posters/oral presentations for scientific meetings, and assessing and assimilating data from journal papers so as to be able to write an essay. A separate session will be provided for MSc students where they will learn how to read a research paper and compose their own abstract. Practical sessions will give you first-hand knowledge and experience of two techniques for assessing cardiovascular functions – Blood pressure & Organ Bath Pharmacology. Masters students will have a slightly more complex blood pressure practical exploring, with the aid of a computer model, how different hemodynamic parameters affect blood pressure.

This module is compulsory for MSc and iBSc Cardiovascular Science students and a recommended option for iBSc students in Physiology as well as Biomedical and Natural Sciences students with a strong background in physiology. It can be taken as an elective by students (including affiliate students) on other degree programmes.

Indicative Lecture list (based on 2023/24 syllabus)

CARDIAC PHYSIOLOGY
Resume of Cardiac Physiology

Cardiac Excitation - Contraction Coupling

Electrocardiogram

Autonomic Control of Heart Function

VASCULATURE, GROWTH & REMODELLING

Vascular Smooth Muscle Contraction

Vascular Potassium Channels

Vascular Endothelium

Animal Models of Cardiovascular Disease

Angiogenesis

The Arterial Wall and Atherosclerosis

RISK FACTORS AND CARDIOVASCULAR DISEASE

Pathology of Systemic Hypertension

Obesity

Sepsis and Circulatory Failure

Endothelium, Inflammation and Vasculitis

HEART DEVELOPMENT & DISEASE

Cardiac Development

Congenital Heart Disease

Pathophysiology of Heart Failure

Ion Channels in Heart Disease


MYOCARDIAL ISCHAEMIA AND PROTECTION
Pathophysiology of Myocardial ischaemia, Protection, Reperfusion and Thrombolysis

Cell Signalling in Myocardial Protection


PROCEDURES IN CARDIOVASCULAR DISEASE

Functional imaging of the Heart

Stem and Gene Therapy for Cardiovascular Repair

Module deliveries for 2024/25 academic year

Intended teaching term: Term 1 Undergraduate (FHEQ Level 6)

Teaching and assessment

Mode of study
In person
Methods of assessment
60% Exam
30% Coursework
10% Labs, practicals, clinicals
Mark scheme
Numeric Marks

The methods of assessment for affiliate students may be different to those indicated above. Please contact the department for more information.

Other information

Number of students on module in previous year
77
Module leader
Professor Lucie Clapp
Who to contact for more information
l.clapp@ucl.ac.uk

Intended teaching term: Term 1 Postgraduate (FHEQ Level 7)

Teaching and assessment

Mode of study
In person
Methods of assessment
15% Viva or oral presentation
25% Coursework
60% Exam
Mark scheme
Numeric Marks

Other information

Number of students on module in previous year
20
Module leader
Professor Lucie Clapp
Who to contact for more information
l.clapp@ucl.ac.uk

Intended teaching term: Term 1 Undergraduate (FHEQ Level 7)

Teaching and assessment

Mode of study
In person
Methods of assessment
15% Viva or oral presentation
25% Coursework
60% Exam
Mark scheme
Numeric Marks

Other information

Number of students on module in previous year
0
Module leader
Professor Lucie Clapp
Who to contact for more information
l.clapp@ucl.ac.uk

Last updated

This module description was last updated on 8th April 2024.