Description
This module covers aspects of genetic mechanisms including non-coding RNA, X-inactivation, imprinting in physiology and cancer, epigenetics in inheritance and development, DNA repair mechanisms, cellular senescence, mitochondrial genetics, DNA origami, clinical genetics and diagnostics, antisense oligonucleotides, gene therapy.
After taking this module you should be able to demonstrate knowledge of:
- genetic mechanisms including DNA replication and repair, the control of gene expression, senescence and apoptosis
- how disruption of these mechanisms can lead to the genesis of chromosomal abnormalities, inherited disorders and cancer
- how gene therapy and antisense oligonucleotides may be applied to treat some of these abnormalities
- the academic and practical aspects involved in the grant application process
You should also have developed critical feedback skills through marking peer assessment.
The module is made up of lectures, tutorials, small group work and student seminar sessions.
Introductory Reading:
Strachan T and Read A (2011) Human Molecular Genetics 4th edition
Module deliveries for 2024/25 academic year
Last updated
This module description was last updated on 19th August 2024.
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