News
The AViDD Sponsored Collaboration with the NIH held a Retreat in San Francisco, Sept 2023
![AViDD retreat group photo, Sept 2023 AViDD retreat group photo, Sept 2023](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-avidd-retreat-group-photo-480x800.jpeg?itok=CV-aBQsX)
![AViDD retreat, Clare, Greg, Oliver, Ziqi, AK, Sept 2023 AViDD retreat, Clare, Greg, Oliver, Ziqi, AK, Sept 2023](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-avidd-retreat-clare-greg-oliver-ziqi-ak.jpeg?itok=iBkG6gGg)
Virtual Virology has made a come back, Sept 2023
![Virtual Virology Virtual Virology](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/virtual_virology_seminar_series_picture_800x480.png?itok=VXmklyaG)
Following a four year pandemic hiatus where ‘Virtual Virology’ took on a much wider meaning, it has returned. Dr Lucy Thorne from Imperial College London hosted three early career PIs:
- Coding Biases and the Recognition of Non-self RNA
Daniel Goncalves Carneiro
- HTLV-1 and T cell tumours: a rare chance to study virus-driven cancer evolution in humans
Aileen Rowan
- Defining the cellular landscape of viral restriction using systems biology
Laura Martin-Sancho
Jolly and Towers labs had their Annual Summer Celebration BBQ, August 2023
![Towers lab summer BBQ. Linran, Oliver, Ziqi, Taylor, Lydia, Dejan, Greg, Ying, Mao, Clare, Jane, Dara, Jas, and Richard, August 2023 Towers lab summer BBQ. Linran, Oliver, Ziqi, Taylor, Lydia, Dejan, Greg, Ying, Mao, Clare, Jane, Dara, Jas, and Richard, August 2023](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-group-photo-img-20230822-wa0042-800x480.jpeg?itok=eoqjGNV4)
![Towers lab Summer BBQ epic food table, August, 2023 Towers lab Summer BBQ epic food table, August, 2023Towers lab Summer BBQ epic food table, August, 2023](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-food-table-img-20230823-wa0001-800x480.jpeg?itok=J2ey6eGd)
![Towers lab Summer BBQ, Lydia, Oliver, Linran, Mao, Ziqi, Jas, Nada, Lucy, Dar, Dejan, Clare, Taylor, Ying. August, 2023 Towers lab Summer BBQ, Lydia, Oliver, Linran, Mao, Ziqi, Jas, Nada, Lucy, Dar, Dejan, Clare, Taylor, Ying. August, 2023](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-lydia-oliver-linran-mao-ziqi-jas-nada-lucy-dara-dejan-clare-taylor-ying-img-20230822-wa0037-800x480.jpeg?itok=5b-0VndS)
![Towers lab Summer BBQ, Oliver, Ziqi, and Jas with snake. August, 2023 Towers lab Summer BBQ, Oliver, Ziqi, and Jas with snake. August, 2023](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-oliver-jas-snake-img20230822-wa0034-800x480.jpeg?itok=LlQx6FsS)
Catching up with Collaborators Al Leslie and Henrik Kloverpris, May 2023
![Henrik, Greg, Clare, Richard, Al. May 2023 Henrik, Greg, Clare, Richard, Al. May 2023](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-al_leslie_and_henrik_kloverpris-img20230518-wa0001-800x480.jpeg?itok=kIshGcAG)
- Jolly and Towers labs attended, May 2023
![AK and Taylor present their posters at Cold Spring Harbor Retrovirus Conference, May 2023 AK and Taylor present their posters at Cold Spring Harbor Retrovirus Conference, May 2023](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/conf-ak-poster-taylor-poster-blue-800-480.png?itok=0J8TYL-d)
![Dejan presents at Cold Spring Harbor Retrovirus Conference, May 2023 Dejan presents at Cold Spring Harbor Retrovirus Conference, May 2023](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/conf-dejan-presenting-img_5200-800x480.jpeg?itok=HveeAGlz)
![Matt, Greg, AK, Clare, and Dejan have a mid conference briefing. Cold Spring Harbor Retrovirus Conference, May 2023 Matt, Greg, AK, Clare, and Dejan have a mid conference briefing. Cold Spring Harbor Retrovirus Conference, May 2023](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/conf-greg-and-jolly-lab-5s6a5835-800x480.jpeg?itok=t1_Xbebf)
![Clare Jolly and Mike Malim catch up at Cold Spring Harbor Retrovirus Conference, May 2023 Clare Jolly and Mike Malim catch up at Cold Spring Harbor Retrovirus Conference, May 2023](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/conf-clare-malim-6c9a6474-800x480.jpeg?itok=e32kiOZS)
![Cold Spring Harbor Retrovirus Conference, May 2023 Cold Spring Harbor Retrovirus Conference, May 2023](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/conf-bbq-5s6a6218-800x480.jpeg?itok=hyBhPSlR)
![Matt, Dejan, AK taking a break at Cold Spring Harbor Retrovirus Conference, May 2023 Matt, Dejan, AK taking a break at Cold Spring Harbor Retrovirus Conference, May 2023](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/lm-matt-dejan-ak-5s6a6351-1-800x480.jpeg?itok=0QiHoKr-)
![Mao, Taylor, AK, Greg, Clare, Lydia, Ying, matt, Dejan take a break during Cold Spring Harbor Retrovirus Conference, May 2023 Mao, Taylor, AK, Greg, Clare, Lydia, Ying, matt, Dejan take a break during Cold Spring Harbor Retrovirus Conference, May 2023](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/conf-mao-taylor-ak-greg-clare-lydia-ying-matt-dejan-eab8b512-8d7f-470c-9a52-8c283e591e9c-800x480.jpeg?itok=CoG_ZrSh)
![AK, Lydia, Taylor, Dejan, Ying, Matt, taking a lunch break at Cold Spring Harbor Retrovirus Conference, May 2023 AK, Lydia, Taylor, Dejan, Ying, Matt, taking a lunch break at Cold Spring Harbor Retrovirus Conference, May 2023](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/conf-ak-lydia-taylor-dejan-ying-matt-lunch-5a874e70-c018-41a6-86ad-2e1878487478-800x480.jpeg?itok=KujwM_II)
![AK, Dejan, Mao, Taylor, Matt, lydia, and Ying heading home from Cold Spring Harbor Retrovirus Conference, May 2023 AK, Dejan, Mao, Taylor, Matt, lydia, and Ying heading home from Cold Spring Harbor Retrovirus Conference, May 2023](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/conf-ak-dejan-mao-taylor-matt-lydia-ying-station-unknown-4-800x480.jpeg?itok=Vh476exH)
![Ying - runner up in the Retrocard competition, Cold Spring Harbor Retrovirus Conference, May 2023 Ying - runner up in the Retrocard competition, Cold Spring Harbor Retrovirus Conference, May 2023](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/conf-retrocards-cold-spring-harbor-blue-800x480.png?itok=FYLc9QSb)
It was great to be back in New York presenting at the Cold Spring Harbor Retrovirus Confernece"
AK Reuschl: Vpr regulates innate immune activation in resting memory T cells
Dejan Mesner: Cell-cell spread triggers a permissivity switch that enhances HIV infection in resting and activated T cells
Taylor Bronzovich: Vpr induction of a tissue-resident phenotype in resting T cells is a broadly conserved feature of lentiviruses
Ying Ying Tan: Vpx degradation of HUSH reveals a protective epigenetic gatekeeper mechanism
Lydia Newton: Synthetic PROTACs based on a depsipeptide macrocycle selectively degrade cyclophilin A and inhibit HIV-1
Maorong Xie: HIV-1 Vpr antagonises interferon by suppressing STAT nuclear transport
Matt Whelan has secured a 5 year Wellcome Trust Early Career Fellowship, May 2023
![Dr Matt Whelan Dr Matt Whelan](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/lm-matt-whelan-800x480.jpg?itok=dhTvI6xK)
Congratulations to Matt Whelan in the Jolly lab who has been awarded a 5-year Wellcome Trust Early Career Fellowship to apply live-cell super-resolution imaging at scale to understand all things HIV and T cells. Well done Matt!
Dejan's paper: '' is published in PNAS, Jan 2023
![Dejan Mesner Dejan Mesner](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/lm-dejan-img_5128-800x480.jpeg?itok=SpgVbMPo)
Our latest work on SARS-CoV-2 VOCs and spike targeting restriction factors, GBP and IFITM proteins, is out now in Proceeding of the National Academy of Sciences 2023. Check out how VOC evolution under different selective pressures has influenced sensitivity to antiviral restriction factors and innate immunity.
Clare and AK attended the , Nov 2022
![Conference pass for 1st South African Workshop on SARS-CoV-2 Variants and Evolution, Nov 2022 Conference pass for 1st South African Workshop on SARS-CoV-2 Variants and Evolution, Nov 2022](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-clare-south-africa-pass-img_4461-800x480.png?itok=jZBE9nk2)
Clare and AK went to South Africa to attend the '1st South African Workshop on SARS-CoV-2 Variants and Evolution' hosted by AHRI in St Lucia (SA). Clare presented 'SARS-CoV-2 VOCs are evolving enhanced innate immune evasion' and AK 'Evolution of enhanced innate antagonism is a recurring SARS-CoV-2 VOC feature and associated with dominance of Omicron lineage BA.5'
Pre-Conference Safari Shenanigans in South Africa, Nov 2022
![Greg, Bec, Petra, Ethan, AK, and Clare on the beach in South Africa, Nov 2022 Greg, Bec, Petra, Ethan, AK, and Clare on the beach in South Africa, Nov 2022](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-south-africa-trip-group-on-the-beach-img-20221028-wa0010-800x480.jpeg?itok=1pZYbXjP)
![The group goes surfing in South Africa, Nov 2022 The group goes surfing in South Africa, Nov 2022](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-south-africa-group-surf-img-20221028-wa0008-800x480.jpeg?itok=YfI3JdzC)
![Petra and AK crocodile spotting in South Africa, Nov 2022 Petra and AK crocodile spotting in South Africa, Nov 2022](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-petra-ak-crocodile-walk-img-20221028-wa0011-800x480.jpeg?itok=X5pYgkn_)
![Petra and AK Shark spotting in South Africa, Nov 2022 Petra and AK Shark spotting in South Africa, Nov 2022](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-south-africa-ak-petra-shark-img-20221028-wa0018-800x480.jpeg?itok=XHW8jtJV)
![Greg, Clare, Bec, AK Petra eating at the beach in South Africa, Nov 2022 Greg, Clare, Bec, AK Petra eating at the beach in South Africa, Nov 2022](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-south-africa-group-meal-img-20221028-wa0019-800x480.jpeg?itok=XaXZ_wFG)
![Greg, Clare, AK, and Petra by the sea in South Africa, Nov 2022 Greg, Clare, AK, and Petra by the sea in South Africa, Nov 2022](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-south-africa-group-pier-shot-img-20221028-wa0021-800x480.jpeg?itok=LfPQscu8)
![AK and a giraffe in South Africa, Nov 2022 AK and a giraffe in South Africa, Nov 2022](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-south-africa-trip-ak-and-giraffe-img-20221028-wa0009-800x480.jpeg?itok=0CpF82Pn)
![Elephants in South Africa, Nov 2022 Elephants in South Africa, Nov 2022](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-south-africa-elephants-img-20221028-wa0014-800x480.jpeg?itok=uBNjHZ5T)
![AK, Greg, Ethan, Bec, Clare, and Petra head off on safari in South Africa, Nov 2022 AK, Greg, Ethan, Bec, Clare, and Petra head off on safari in South Africa, Nov 2022](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-south-africa-trip-group-safari-img-20221028-wa0007-800x480.jpeg?itok=sfUiwtAW)
![Petra and AK take a final walk on the beach in South Africa, Nov 2022 Petra and AK take a final walk on the beach in South Africa, Nov 2022](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-south-africa-trip-petra-ak-beach-img-20221028-wa0006-800x480.jpeg?itok=Mk04GDXw)
NIH Funding for the Collaboration with the Krogan lab has been confirmed, July 2022
![news-Nevan Krogan, Greg Towers and Clare Jolly catching up in London Oct 2022 news-Nevan Krogan, Greg Towers and Clare Jolly catching up in London Oct 2022](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-nevan-krogan-visit-2022-nevan-greg-clare-800x480.jpeg?itok=2lA0Q6AD)
The Jolly and Towers labs are part of an NIH AViDD funded international collaboration. The goal of this collaboration is to produce potent inhibitors that act against SARS-CoV-2. It’s a huge collaboration involving many international laboratories and will cover everything from inhibitor design, library screening, and investigating structure activity relationships through to detailed studies of inhibitor mechanism.
Ann-Kathrin’s Vpr paper is published in Cell Reports, April 2022
![Dr Ann-Kathrin Reuschl Dr Ann-Kathrin Reuschl](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/lm-ak-20180929_105209-800x480.jpeg?itok=JLvJlETr)
![Reuschl et al, cell 2022 abstract graphic, April 2022 Reuschl et al, cell 2022 abstract graphic, April 2022](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-ak-cell-paper-abstract-graphic-2022.png?itok=O0i-oTVT)
Ann-Kathrin’s paper showing how HIV-1 uses its Vpr to reprogram resting T cells to adopt a tissue-resident like phenotype is .
'Evolution of enhanced innate immune evasion by SARS-CoV-2' is published in Nature, Dec 2021
![Thorne et al, Nature 2021 Thorne et al, Nature 2021](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-thorne-et-al-nature-2021-800x480.png?itok=h03AW5zx)
![Lucy, Matt, Lorena and AK, June 2021 Lucy, Matt, Lorena and AK, June 2021](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-the-sars-4-800x480.png?itok=k6S04inC)
Lucy and AK's work with Lorena and Mehdi Bouhaddou from the Krogen Lab on
Clare and Nevan spoke with , June 2021
![Clare is interviewed by Nature about the Alpha variant dominance, June 2021 Clare is interviewed by Nature about the Alpha variant dominance, June 2021](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-nature-article-alpha-dominance-800x480.png?itok=kbEx1NoA)
![Clare working in containment, June 2021 Clare working in containment, June 2021](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/cvd-clare-window_27a7124-800x480.jpeg?itok=SVqk-R4g)
...
'' is on BioRxiv and The New York Times has published an article on it, June 2021
![Lucy, Matt, Lorena and AK, June 2021 Lucy, Matt, Lorena and AK, June 2021](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-the-sars-4-800x480.png?itok=k6S04inC)
![NYT alpha variant article, June 2021 NYT alpha variant article, June 2021](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-nyt-alpha-variant-article-800x480.png?itok=E-9jQQcN)
Our latest paper demonstrating our work on how the Alpha variant evades early immune responses is on and it has attracted the attention of the .
Tafhima's paper is out in PNAS, May 2021
![Haider et al, PNAS, May 2021 Haider et al, PNAS, May 2021](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/p-tafhima-pnas-paper-480x800.png?itok=TWdZcnqW)
![Tafhima Haider Tafhima Haider](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/tafhima-800x480.jpeg?itok=3tYT8VtV)
ABC News joined AK and Lucy as they met with Lorena and the rest of our American collaborators on Teams, March 2021
![ABC News joined the Jolly, Towers and Krogen labs at their weekly meeting, March 2021 ABC News joined the Jolly, Towers and Krogen labs at their weekly meeting, March 2021](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/pe-abc-news-krogan-collaboration-800x480.png?itok=_vWQXtKi)
![AK, Lucy and Lorena at Krogan/Jolly/Towers lab meeting recorded by ABC News, March 2021 AK, Lucy and Lorena at Krogan/Jolly/Towers lab meeting recorded by ABC News, March 2021](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/pe-abc-video-of-krogan-lab-meeting-800x480.png?itok=ozN6vJZG)
is out on BioRxiv! Jan 2021
![Dr Ann-Kathrin Reuschl trains researchers in SARS-CoV-2 work, 2020 (photo courtesy of Nick David www.nickdavid.co.uk) Dr Ann-Kathrin Reuschl trains researchers in SARS-CoV-2 work, 2020 (photo courtesy of Nick David www.nickdavid.co.uk)](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/cvd-ak_27a7209-800x480.jpeg?itok=rmVDRdBi)
'' on BioRxiv, Jan 2021
![AK Reuschl, Lucy Thorne and Lorena Alvarez-Zuliana researching SARS-CoV-2, Jan 2021 AK Reuschl, Lucy Thorne and Lorena Alvarez-Zuliana researching SARS-CoV-2, Jan 2021](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-ak-lucy-lorena-800x480.png?itok=bB-gOeP9)
![Reuschl et al Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant, Jan 2021 Reuschl et al Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant, Jan 2021](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-reuschl-et-al-host-directed-therapies-variant-800x480.png?itok=IQpN2rh8)
The first study of the full-length B.1.1.7 variant virus, we find two host-directed drugs to possess similar antiviral activity against both the early-lineage SARS-CoV-2 and the B.1.1.7 variant. Read the results of alongside the Krogan lab at UCSF.
AK, Lucy, Lorena and Matt's paper is published on the BioRxiv preprint server, Dec 2020
![Dr Ann-Kathrin Reuschl trains researchers in SARS-CoV-2 work, 2020 (photo courtesy of Nick David www.nickdavid.co.uk) Dr Ann-Kathrin Reuschl trains researchers in SARS-CoV-2 work, 2020 (photo courtesy of Nick David www.nickdavid.co.uk)](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/cvd-ak_27a7209-800x480.jpeg?itok=rmVDRdBi)
![Thorne et al 2021, BioRxiv Thorne et al 2021, BioRxiv](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-thorne-et-al-feb-2021-800x480.png?itok=OR92AJVl)
All the hours and hard work in the cat3 lab have paid off. AK, Lucy, Lorena, and Matt's paper is published on the BioRxiv server.
Our collaborative work is publlished in Leukemia, March 2020
![O'Nions et al 2020. Fig 1 Temporal dynamics and anti-viral function of SARS-CoV-2 antibody responses in haematological malignancy O'Nions et al 2020. Fig 1 Temporal dynamics and anti-viral function of SARS-CoV-2 antibody responses in haematological malignancy](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/pub-onions-et-al-2020-800x480.png?itok=KCNCzHsR)
Jenny O'Nions, Luke Muir, Jiexin Zheng, Chloe Rees-Spear, Annachiara Rosa, Christopher Earl, Peter Cherepanov, Rajeev Gupta, Asim Khwaja, Clare Jolly, Laura E McCoy
The Jolly lab has re-opened for SARS-CoV-2 work, April 2020
![Dr Ann-Kathrin Reuschl trains researchers in SARS-CoV-2 work, 2020 (photo courtesy of Nick David www.nickdavid.co.uk) Dr Ann-Kathrin Reuschl trains researchers in SARS-CoV-2 work, 2020 (photo courtesy of Nick David www.nickdavid.co.uk)](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/cvd-ak_27a7209-800x480.jpeg?itok=rmVDRdBi)
We are working closely with the Towers, Selwood and Noursadeghi labs (UCL) to address the following questions:
· How does the virus trigger innate and proinflammatory responses across different cell types in vitro?
· Which pathways lead to proinflammatory cytokine secretion and cell death, as observed in severe COVID-19 patients?
· How do the responses observed in vitro compare to those seen in vivo?
· How do the innate responses influence immune crosstalk and T cell functions associated with immunopathology in severe COVID-19 patients?
· Can we identify specific pathways and inhibitors to modulate innate and immune crosstalk to reduce pro-inflammatory responses and cell death?
· Which viral proteins activate or antagonise innate responses?
· Which restriction factors target SARS-CoV-2 and do these contribute to innate immune signalling?
We have been busy supporting the work of other groups at 911 by getting our CL3 labs operational for SARS-CoV-2, and training and supervising new users:
![Dr Clare Jolly trains researchers in SARS-CoV-2 work, 2020 (photo courtesy of Nick David www.nickdavid.co.uk) Dr Clare Jolly trains researchers in SARS-CoV-2 work, 2020 (photo courtesy of Nick David www.nickdavid.co.uk)](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/cvd-clare-mashiro-cl3-training_27a6977-800x480.jpeg?itok=LM0_mN1q)
![Dr Ann-Kathrin Reuschl trains researchers in SARS-CoV-2 work, 2020 (photo courtesy of Nick David www.nickdavid.co.uk) Dr Ann-Kathrin Reuschl trains researchers in SARS-CoV-2 work, 2020 (photo courtesy of Nick David www.nickdavid.co.uk)](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/cvd-ak-kaylee-cl3-training_27a7160-800x480.jpeg?itok=mhumox5r)
Dejan's paper is published in Proceedings of the National Academy of Sciences of the United States of America, March 2020
Mesner D, Hotter D, Kirchhoff F, Jolly C. . Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7382-7391. doi: 10.1073/pnas.1921135117. Epub 2020 Mar 16.
Clare presented at the. January 2019
![Dr Clare Jolly pesents at the 1st Max Planck Society Workshop on HIV Reservoirs and Evolution, St Lucia, South Africa Dr Clare Jolly pesents at the 1st Max Planck Society Workshop on HIV Reservoirs and Evolution, St Lucia, South Africa](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-clare-presents-in-africa-img-20190122-wa0006-800x480.jpeg?itok=tFhBk53v)
![Elephant spotting on safari following the 1st Max Planck Society Workshop on HIV Reservoirs and Evolution, St Lucia, South Africa. Elephant spotting on safari following the 1st Max Planck Society Workshop on HIV Reservoirs and Evolution, St Lucia, South Africa.](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-on-safari-in-africa-img-20190124-wa0000-800x480.jpeg?itok=zjRDGwfU)
Clare presented on 'Cell - Cell spread of HIV-1' and rounded the conference off with a safari with Greg, Ravi, and Laura.
Infection and Immunity's Christmas Party, December 2018
![Awesome evening captured by AK. The Infection and Immunity Christmas Party 2018 Awesome evening captured by AK. The Infection and Immunity Christmas Party 2018](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-i-andi-christmas-party-2018-20181214_014000-800x480.jpeg?itok=EYONpYcA)
Jolly Lab Retreat in Amsterdam with the Towers Lab, December 2018
![Towers and Jolly Labs on retreat in Amsterdam 2018 Towers and Jolly Labs on retreat in Amsterdam 2018](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-retreat-group-photo-chill-area-dsc_3471-800x480.jpeg?itok=QTuThAjG)
.
![The Jolly lab group photo, Amsterdam. December 2018 The Jolly lab group photo, Amsterdam. December 2018](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-retreat-jolly-lab-photo-800x480_0.jpeg?itok=Xlo7yJVm)
We attended the Frontiers of Retrovirology conference in Leuven, Belgium, September 2018.
![Frontiers of Retrovirology conference in Leuven, Belgium Frontiers of Retrovirology conference in Leuven, Belgium](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-conference-dinner-retrovirology-3-800x480.jpeg?itok=6cbpgi98)
Jolly Lab win at the Feathers pub quiz, 2018
![A win for the Jolly lab at the Feathers pub quiz A win for the Jolly lab at the Feathers pub quiz](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-pubquiz_win_2018-800x480.jpeg?itok=1-2_aWs5)
The Lab was at the the 10th Blizard Institute HIV Symposium, June 2018
Setting up the draw for the department World Cup sweepstake, 2018
The department was swept up in World Cup fever thanks to an ingenious system devised by the Jolly lab of countries written on agar. You have to grow your bacteria to see who you drew!
Microbiology Society Conference, 2018
![The Jolly lab attends the Microbiology Society Conference, 2018 The Jolly lab attends the Microbiology Society Conference, 2018](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-microbiolsoc_conference_2018-800x480.jpeg?itok=ImHHu7qy)
Infection and Immunity divisional Christmas Party, December 2017
![The Jolly Lab at the 2017 Infection and Immunity divisional party The Jolly Lab at the 2017 Infection and Immunity divisional party](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-iandi_xmas_2017-800x480.jpeg?itok=NkoGI_DA)
Christmas celebrations with the Towers lab at 'Watch Me', December 2017
![Christmas celebrations with the Towers lab Christmas celebrations with the Towers lab](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-towers_xmas_2-800x480.jpeg?itok=fjr6GjyM)
WOHL Christmas Dinner, December 2017
![WHOL Christmas dinner WHOL Christmas dinner](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-wohl_xmas_2017_2-800x480.jpeg?itok=JR_FwmBN)
Halloween celebrations with the Towers lab, October 2017
Halloween dressing up - a character that shares your initails......
Towers lab picnic in Regent's Park, August 2017
![Towers lab picnic in Regent's Park 2017 Towers lab picnic in Regent's Park 2017](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-picnic-2017-dsc_2133-800x480.jpeg?itok=o3NJK-XV)
Our Latest Paper is Published in Cell Reports, 2017.
![The Jolly lab has had their paper “HIV-1 activates T cell signaling independently of antigen to drive viral spread” published in Cell Reports. The Jolly lab has had their paper “HIV-1 activates T cell signaling independently of antigen to drive viral spread” published in Cell Reports.](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-graphical-abstract-from-len-et-al-cell-reports-2017-800x480.jpg?itok=35wEsm2Z)
Infection and Immunity Christmas Party, December 2016
Looking good at Infection and Immunity's Christmas party.
WOHL Christmas dinner, 2016
![WHOL Christmas dinner WHOL Christmas dinner](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-wohl_christmas_2016-800x480.jpeg?itok=L7LL_2jD)
Dr Shimona Stirling leaves the Jolly lab, 2016
![Dr Shimona Stirling leaves the Jolly lab for a post at Nature Dr Shimona Stirling leaves the Jolly lab for a post at Nature](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-shimona_leaving_2016-800x480.jpeg?itok=wqBf6nhp)
Towers lab picnic in Regents Park, August 2016
![Towers lab picnic in Regent's Park 2016 Towers lab picnic in Regent's Park 2016](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-picnic-2016-img_20160804_163413344-800x480.jpeg?itok=KQMy96z8)
Two generations of HIV scientists meet, 2016
![Two generations of HIV scientists meet: Members of the Jolly lab with Françoise Barré-Sinoussi after the UCL Prize Lecture for Clinical Science 2016 Two generations of HIV scientists meet: Members of the Jolly lab with Françoise Barré-Sinoussi after the UCL Prize Lecture for Clinical Science 2016](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-2-generations-jolly-lab-800x480.jpg?itok=uAZOpkRu)
Shimona Starling wins 1st prize at the Colloquium, 2015
![Shimona Starling won 1st prize at the PhD colloquim Shimona Starling won 1st prize at the PhD colloquim](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-shimona-prize-dscf0464-800x480.jpeg?itok=0M-O9j7e)
Clare Secures a further 5 years funding, 2015
![Dr Joe Grove, Prof Greg Towers, Prof Ravi Gupta and Dr Clare Jolly celebrate their Wellcome Trust awards. Dr Joe Grove, Prof Greg Towers, Prof Ravi Gupta and Dr Clare Jolly celebrate their Wellcome Trust awards.](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-joe-greg-ravi-clare-grant-celebrations-p1020384-800x480.jpeg?itok=8frIpyLR)
Celebrations were held in the UCL Quad to congratulate Clare along with Dr Joe Grove, Prof Greg Towers and Dr Ravi Gupta who all secured Wellcome Trust grants.
Clare's Image on the cover of Journal of Virology, Jan 2015
![Dr Clare Jolly's image graces the cover of the Journal of Virology, Jan 2015 Dr Clare Jolly's image graces the cover of the Journal of Virology, Jan 2015](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/jolly-publications-teaser.png?itok=CHtbFMqJ)
Elisabetta Spent 6 weeks in Sierra Leone, Feb 2015
![Sample reception at the Ebola diagnostic laboratory, Port Loko, Sierra Leone Sample reception at the Ebola diagnostic laboratory, Port Loko, Sierra Leone](/jolly-lab/sites/jolly_lab/files/styles/non_responsive/public/news-siera-leone-dsc00106-800x480.jpg?itok=wDuees_G)
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