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Centre for Advanced Biomedical Imaging

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Ultrasound

All info from VisualSonics website

Ultrasound with high image quality, increased frame rates, superb contrast, unrivalled resolution and a wide field of view. The system is easy to use, non-invasive and fast, providing extremely high throughput when needed.

Contact: d.stuckey(at)ucl.ac.uk; a.david(at)ucl.ac.uk

Applications

    • b-mode for chamber volumes, ejection fraction and LV mass
    • m-mode and anatomical m-mode for fractional shortening
    • pulse wave Doppler for atrial, aortic and carotid flow
    • colour and power Doppler for blood flow quantification & anatomical identification
    • needle guidance for closed chest intracardiac injections

    • 3D tumour volumes
    • Tumour perfusion

  • Developmental research

    • 3D imaging of embryos in situ
    • Monitoring brain development
    • Measuring cardiac function

听

Vevo 2100 Ultrasound system

听

Imaging stage

Imaging modes

  • Superb B-Mode (2D) imaging for anatomical visualization and quantification, with enhanced temporal resolution with frame rates up to 740 fps (in 2D for a 4x4 mm FOV), and enhanced image uniformity with multiple focal zones
  • M-Mode for visualization and quantification of wall motion in cardiovascular research, single line acquisition allows for the very high-temporal (1000 fps) resolution necessary for analysis of LV function
  • Anatomical M-Mode for adjustable anatomical orientation in reconstructed M-Mode imaging; software automatically optimizes field of view for maximum frame rate

mmode

M-mode imaging of mouse left ventricle

  • Pulsed-Wave Doppler Mode (PW) for quantification of blood flow
  • Color Doppler Mode for detection of 听blood vessels including flow directional information and mean velocities; as well as for identification of small vessels not visible in B-Mode

Doppler

Color Doppler imaging in the mouse spleen

  • 3D-Mode Imaging for anatomical and vascular visualization, when combined with either B-Mode, Power Doppler Mode or Nonlinear Contrast Imaging; allows for quantification of volume and vascularity within a defined anatomical structure

3dus

3D B-Mode imaging of orthotopic hepatoma tumor. Dark blue tumor volume. Light blue liver, Orange kidney

See the听collaborations听page for information on access to this system