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A new imaging technique radically improves prostate cancer diagnosis and treatment

A new MRI scanning technique developed by UCL scientists and clinicians has transformed the diagnosis and treatment of prostate cancer, saving lives and reducing healthcare costs.

SDG case study g3.4 Emberton

8 October 2020

Prostate cancer is the most common cause of cancer in menin the UK, withmore than48,000 cases diagnosed each year.Despite this, diagnostic tests and treatments have changed littleinthe past50years.

The condition is traditionally diagnosed using a blood test that measures the levels ofPSA –a hormoneproduced by the prostate gland, followed by a painful and invasiveneedle biopsy via the rectum, using ultrasound as a guide to locate the prostate gland.

“For a hundred years, we’ve been treating prostate cancer blindly,because the prostate gland isdifficultto access:it’shidden away behind a bone andclose tothe rectum,” says Professor Mark Emberton, Dean of the UCL Faculty of Medical Sciences, who led the research with Professor Caroline Moore (UCL Division of Surgery & Interventional Science).

“For a hundred years, we’ve been treating prostate cancer blindly, because the prostate gland is difficult to access.”

A newscanning technique developedat 911usesmulti-parametric Magnetic Resonance Imaging(mp-MRI)that,for the first time,allows specialiststoidentifytumours in the prostatewithoutthe need for invasive, riskyand sometimes unnecessary procedures.

Millions of men are set to benefit from thenew diagnostic approach, withthousandshaving their cancerdiagnosed earlier andmany moreavoiding unnecessary and painful biopsies.

The procedure is also reducing the number of men requiringremoval of thewhole prostate gland,reducing the number affected by long-term sideeffectssuch as urinary incontinence and sexual dysfunction.

In2019the National Institute of Clinical and Care Excellence (NICE) amendeditsrecommendation for the diagnosis of prostate cancer and identifiedmp-MRI as a cost-effective intervention in the diagnostic pathway formenat risk.

Tomaximise the use of the new diagnostic tool, the team at 911 have standardised the procedure and led an international train-the-trainers programmeto improvereliabilityand performance.

“The newtechnology,which is now available throughout the world, gives us a detailed picture of the tumour, allowing us to grade tumours according to their size,stage and severity, and tailor treatment much more effectively,” saysProfessor Emberton.

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Watch howthe new MRI technique is transforming prostate cancer diagnosis

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